Alexander Knuth, M.D.
National Center for Cancer Care and Research
Research by Alexander Knuth, M.D., focuses on the development of innovative immune-based treatment modalities for cancer patients. Following a research fellowship with Drs. Lloyd J. Old and Herbert F. Oettgen at Memorial Sloan-Kettering Cancer Center from 1978 to 1981, Dr. Knuth ,at the University of Mainz, Germany, contributed to the research that identified and cloned the first human cancer antigen/gene, now understood as part of the MAGE gene family. Since then, Dr. Knuth has led numerous clinical trials of cancer vaccines and immunotherapies and has helped pioneer new immune monitoring technologies including ELISPOT to test antigen-specific T cell responses.
Dr. Knuth received his M.D. in 1973 from the Free University Berlin, Germany, and completed a clinical residency and fellowship in internal medicine, hematology/oncology at Krankenhaus Moabit, West Berlin, Germany.