Michael L. Dustin, Ph.D.
NYU Langone Medical Center
New York, NY
Michael Dustin, Ph.D., is the Muriel G. and George W. Singer Professor of Molecular Immunology at the New York University Langone Medical Center, where his work focuses on understanding the importance of the immunological synapse for T cell activation in health and disease. His research on the regulation and organization of the immunological synapse began in 1985 when, as a graduate student with Timothy A. Springer at Harvard Medical School, he discovered ICAM-1. His subsequent graduate work focused on CD2/CD58 interaction, ICAM-1 regulation by cytokines, LFA-1 regulation by T cell receptor, and the cloning of ICAM-2. Since then, he has made important contributions, including the identification of an antigen-dependent stop signal for T cells with Dr. Emil Unanue, and a description of molecular segregation in the immunological synapse, with Drs. Andrey Shaw, Paul Allen, and Mark Davis.
Dr. Dustin received his Ph.D. in Cell and Developmental Biology in 1991 from Harvard University, and carried out postdoctoral training from 1990 to 1993 with Dr. Stuart Kornfeld at Washington University School of Medicine, where he worked on molecular biology approaches to analysis of protein-protein recognition in the secretory pathway. He joined the faculty at Washington University as an assistant professor in the Department of Pathology in 1993. In 2001, he moved to the Skirball Institute of Biomolecular Medicine at New York University School of Medicine, where he was the Irene Diamond Associate Professor of Immunology until 2006, when he was promoted to full professor. Dr. Dustin is a fellow of the American Association for the Advancement of Science.