About CRI

William E. Paul, M.D.

National Institutes of Health
Bethesda, MD

William E. Paul, a leading immunologist, is well known for his discovery of interleukin-4 (IL-4) and for an extensive body of research that includes the purification of IL-4 and the characterization of its receptor and its signaling mechanisms.  Dr. Paul served as the director of the federal Office of AIDS Research (OAR) from February 1994 until October 1997. Under Dr. Paul’s leadership, the office implemented new broad authorities provided by the NIH Revitalization Act of 1993 to expand the role of the OAR in determining national AIDS research policy. During his tenure, the OAR developed the first annual comprehensive plan and unified budget for all NIH-sponsored AIDS scientific activities. After leaving his post at the OAR, Dr. Paul returned to full-time research at his laboratory in the National Institute of Allergy and Infectious Diseases, redirecting his scientific efforts to searching for a safe and effective HIV vaccine and for new approaches to vaccine development.

Dr. Paul has been the recipient of numerous honors and awards, including the Max Delbrück Medal, the Abbott Laboratories Award in Clinical and Diagnostic Immunology, and Lifetime Achievement Awards from the American Association of Immunologists and the International Cytokine Society.  A member of the National Academy of Sciences and its Institute of Medicine, Dr. Paul is the former president of the American Association of Immunologists and of the American Society of Clinical Investigation.  Dr. Paul is a fellow of the American Academy of Arts and Sciences.