Clinic & Laboratory Integration Program (CLIP) Apply for the Clinic and Laboratory Integration Program Grant CRI Grants Portal CLIP supports pre-clinical and translational research that can be directly applied to optimizing cancer immunotherapy in the clinic. CRI CLIP Grants are awarded to qualified scientists exploring clinically relevant questions aimed at improving the effectiveness of cancer immunotherapies. ADDITIONAL OPPORTUNITIES: In partnership with the Chordoma Foundation (CF), CRI also invites LOIs focused on topics related to accelerating the development of effective treatments and ultimately a cure for chordoma, a rare type of cancer that occurs in the bones of the skull base and spine. Please be advised that CF has chordoma models and banked tumor samples (including a new TMA consisting of 95 chordoma specimens) that are available to the research community. Successful applications in this area will be co-funded by CRI and CF. In partnership with the Kidney Cancer Association (KCA), CRI invites LOIs specifically focused on topics related to accelerating the development of effective immunotherapies for kidney cancer. Successful applications in this area will be co-funded by CRI and KCA. Overview The Cancer Research Institute mission is to save more lives by fueling the discovery and development of powerful immunotherapies for all types of cancer. It funds research aimed at furthering the development of immunological approaches to the diagnosis, treatment, and prevention of cancer. The development of new and effective cancer treatment requires the translation of basic laboratory discoveries into novel therapies that can be tested in patients. This area of translational research—where laboratory findings move into clinical testing, and where questions from clinical studies are brought back into the lab—is critical to bringing new and better immunotherapies to patients. The Cancer Research Institute established CLIP to support investigators who are studying critical topics at the intersection of laboratory and clinical research Financial Information CRI CLIP Grants provide up to $150,000 per year for two years. The funds may be used for salary, technical assistance, supplies, capital equipment, or scientific travel. CRI does not provide funds for indirect costs. Payments are made quarterly in U.S. currency to the host institution. Deadlines The process for applying for a CRI CLIP Grant consists of two parts: Letter of Intent Invited Application The deadline for the receipt of the Letter of Intent is December 1. Candidates will be notified by the end of January whether they have been invited to submit a full grant proposal. The full application is due March 1. If these deadlines fall on the weekend, applications will be accepted the following Monday. Applications are due by 5 p.m. Eastern Time on these dates. The earliest an award can activate is July 1. Awards activate on the first of the month. Eligibility Candidates for a CRI CLIP Grant must hold a faculty appointment as a tenure-track assistant professor (or higher rank) at the time of award activation. If not, documentation from their institution must accompany the Letter of Intent indicating they will hold the position of assistant professor (or higher rank) by the time of award activation. CRI has no citizenship restrictions, and research supported by the award may be conducted at medical schools and research centers in the United States or abroad. Please note that CRI CLIP Grants do not support research at for-profit institutions. Instructions for Applying Letters of intent must be submitted electronically. Once you access the application, you will be asked to create a user account unique to you, which will catalogue all applications you submit to CRI. If you have submitted a grant application to CRI in the past, please login with your existing user account. Supporting Materials After you have filled out all required fields on the online form, you will be asked to upload the following four (4) items as individual PDF documents. An initial research concept (succinct description of the proposed research, description of the relevance of the proposed research to cancer immunology, description of how your proposed project bridges laboratory and clinical discovery), not to exceed 3 pages. Brief description of your current research. Curriculum vitae and bibliography (limit bibliography to past 5 years or publications relevant to proposed research). Notes: Applications exceeding stated page limits will be disqualified. Only PDF documents will be accepted. All files must be submitted individually on the attachments page of the online application. When you have finished uploading the attachments, click “Submit.” You will receive a notice confirming that you have successfully submitted your Application Form. Immediately after, an automated notification from CRI will be sent to your email address, also confirming submission. If you encounter problems uploading your attachments, email them to [email protected]. Be sure to note the application number, which will be assigned to you at the time of submission. Online applications will be accepted until 5 p.m. Eastern Time on the deadline date. If the deadline falls on the weekend, applications will be accepted until the close of business that following Monday. We strongly suggest submitting your applications as early as possible to provide ample time in case your application is incomplete. Incomplete applications will not be considered. Formatting Guidelines: Any documents you attach to your online application form must be typed single-space using a 12 point or larger font size. Award Terms and Conditions All awardees must adhere to the terms of this award. Please note: The Cancer Research Institute will not modify the terms of its policies at the request of individual institutions. Policies have been approved by our Board of Trustees, and we do not have the resources to negotiate separately with the many institutions that receive our support. Application Deadlines Letter of Intent December 1 iNVITED Full Application March 1 (If a deadline falls on the weekend, applications are due the following Monday.) Application Resources Terms and Conditions Invention Disclosure Form Annual Invention Update Form Standard Revenue Sharing Agreement Frequently Asked Questions