Liuhui Fu, PhD, Postdoctoral Fellow New York University School of Medicine Area of Research: All Cancers Liuhui Fu, PhD, is a postdoctoral fellow at the NYU Grossman School of Medicine, where he investigates the role of RORγt+ antigen-presenting cells (RORγt-APCs) in immune tolerance. His research explores how these specialized cells prevent harmful immune responses to gut bacteria and dietary proteins by inducing regulatory T cells (pTregs). However, this same mechanism may also contribute to immune evasion in cancer, allowing tumors to escape detection by enhancing pTreg activity. “My academic and research endeavors are deeply rooted in exploring the sophisticated interplay between environmental stimuli and the immune system,” Dr. Fu explains, a focus that has shaped his work across mucosal immunology, tumor biology, and metabolic regulation. Dr. Fu’s current research employs cutting-edge lineage-tracing models to uncover the origins and functions of RORγt-APCs. By elucidating how these cells mediate both food tolerance and tumor tolerance, he aims to develop novel therapies that modulate immune responses. His findings could lead to treatments that enhance tolerance in food allergies while breaking immune suppression in cancer, improving immunotherapy outcomes. A rising leader in immunology, Dr. Fu’s research has already made significant contributions, including demonstrating how gut microbial metabolites enhance CD8+ T cell function in cancer therapy and uncovering novel metabolic pathways in allergic immune responses. With a long-term goal of leading an independent research lab, Dr. Fu is committed to advancing our understanding of immune regulation and translating these discoveries into innovative treatments for allergic and inflammatory diseases, as well as cancer. Projects and Grants Characterization of Tolerogenic Antigen-Presenting Cells Inducing Peripheral Immune Tolerance New York University Grossman School of Medicine| All Cancers, Allergy| 2025 | Dan Littman, MD, PhD
