Benjamin Izar, MD, PhD, CRI Lloyd J. Old STAR Columbia University Area of Research: All Cancers Dr. Benjamin Izar’s work leverages natural and synthetic protein variants to enhance T cell function in cancer immunotherapy. His team’s cutting-edge methods generate thousands of variants to improve CAR T and TIL therapies, showing promising results in pre-clinical mouse models of melanoma and leukemia. Dr. Izar aims to address resistance mechanisms and enhance the efficacy of cellular therapies for solid and hematologic cancers. Projects and Grants Enhancing Cellular Cancer Immunotherapies through Massively Parallel Discovery of Novel Protein Variants Coupled with Functional Single-Cell Multi-Omics Columbia University | All Cancers | 2024
